Wolfgang Kreyling, Ph.D., is a biophysicist coordinating all aerosol-related research within the Focus Network Nanoparticles and Health of the Helmholtz Center Munich (HMGU) spanning R&D work over five HMGU-institutes ranging from material sciences to toxicology and epidemiology. He is deputy director of the HMGU-Institute for Inhalation Biology. He chairs the R&D program on dosimetry of ultrafine aerosol particles and engineered nanoparticles in the respiratory tract and secondary target organs like the cardiovascular and the central nervous system. In 2004 he received the Paula and Richard von Hertwig-Award and in 2007 the Jurai Ferin Award of the International Society for Aerosols in Medicine.
Dr. Kreyling obtained his M.S. (diploma) in physics at the Ludwig-Maximillians-University of Munich, Germany, and his Ph.D. at the Technical University of Munich. In 1985/86 he spent a sabbatical at the Harvard School of Public Health in Boston, MA, USA. Until recently Dr. Kreyling was Past-President of the International Society for Aerosols in Medicine (ISAM). He is member of various other international scientific societies, serves as a member of several European committees and action plans and he is editorial board member of several international aerosol and nanotechnology related journals.
His research interests range from aerosol sciences and nanoparticle technology to biophysics of the lungs reaching from the characterization of ambient aerosols to particle dosimetry and nanoparticle lung interactions on the level of the entire organism, cells like alveolar macrophages, and molecular compounds. Recently, in a DFG funded collaborative effort with the Universities of Marburg and Gießen his research is aimed at the sustainable development of nanocarriers for drug delivery to the lungs. In an NIH funded research project he investigates differences of aerosol particle deposition in the various regions of new-born versus adult rats; and in an EU funded research project he studies dosimetric aspects of accumulation of engineered nanoparticles in various secondary target organs such as liver, kidneys, brain, heart and reproductive organs after respiratory, gastric or blood intake. He has co-authored more than 150 peer-reviewed publications in international journals and books.
Möller W, Felten K, Sommerer K, Scheuch G, Meyer G, Meyer P, Häussinger K, Kreyling WG. Deposition, retention, and translocation of ultrafine particles from the central airways and lung periphery. Am J Respir Crit Care Med.2008 177, 426-432.
Takenaka S, Karg E, Kreyling WG, Lentner B, Möller W, Behnke-Semmler M, Jennen L, Walch A, Michalke B, Schramel P, Heyder J, Schulz H. Distribution pattern of inhaled ultrafine gold particles in the rat lung. Inhal Toxicol. 2006 18, 733-740.
Meiring JJ, Borm PJ, Bagate K, Semmler M, Seitz J, Takenaka S, Kreyling WG. The influence of hydrogen peroxide and histamine on lung permeability and translocation of iridium nanoparticles in the isolated perfused rat lung.Part Fibre Toxicol. 2005 2, 3-16.
