Creation of protocols for a limited number of toxicology tests on a small number of representative nanoparticles to enable a ‘round robin’ study in which identical results will be sought. This will involve at least the use of nanomaterials and biologicals from a common source and a single set of protocols.

• The implementation of a round robin laboratory set of tests based on these protocols

• Ongoing and further development of in vitro and in vivo protocols that take into consideration nanomaterial physicochemical properties and quantitative structure function relationships at the nanobio interface.